Research project led by Bailey Hanna, MS, RDN - no affiliate links, ads or sponsored products.
The Db symptom type is one of the most prevalent. So we were excited to see the findings. Unexpectedly, we saw some unusual results for the Db symptom type with majority of probiotics underperforming. In fact, out of the 44 probiotics in our database, only 5 showed moderate support for diarrhea. More notably, only Lactospore and Unique IS-2 also provided moderate or greater relief for bloating. On the positive side, this finding is helpful as it narrows down the options and makes it easier to select the a suitable probiotic for your patient.
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Statistically significant improvement and a Cohen’s d or h of ≥ 1.0
Statistically significant improvement and a Cohen’s d or h of 0.5 – 1.0
Statistically significant improvement and a Cohen’s d or h of <0.5
No statistically significant effect
Not studied
Adverse effects measured
Out of the 2 leading strains, Lactospore has a slight edge in potential bloating relief, but Unique IS-2 has slightly higher overall evidence quality. In situations like this, it can be worth further filtering based on Global IBS Symptoms relief and considering an n=1 experiment protocol for your patient.
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