Research project led by Bailey Hanna, MS, RDN - no affiliate links, ads or sponsored products.
About
< Back
About
Close
View entire database
Access Database
Compare probiotics:
Our story
Team
FAQ
Contact
Research Notes
< Back
Research Notes
Close
View entire database
Access Database
Compare probiotics:
Methodology
Effect Size Explainer
Symptom Categorization
Professional Guidelines
Compare Probiotics
< Back
Compare Probiotics
Close
View entire database
Access Database
Compare probiotics:
Based on Symptoms
Diarrhea
Constipation
Bowel Habits
Global IBS Symptoms
Pain / Discomfort
Bloating / Distention
Gas / Flatulence
Nausea / Vomiting
Mental Health
Quality of Life
Based on Multi Symptoms
Diarrhea + Constipation
Diarrhea + Pain
Diarrhea + Bloating
Diarrhea + Gas
Diarrhea + Nausea
Diarrhea + Mental Health
Constipation + Pain
Constipation + Bloating
Constipation + Gas
Constipation + Nausea
Constipation + Mental Health
Diarrhea + Constipation + Pain
Diarrhea + Constipation + Bloating
Diarrhea + Constipation + Gas
Diarrhea + Constipation + Nausea
Diarrhea + Constipation + Mental Health
Based on Strains/Blends
35624
ATCC 55730
Bio-25
Biogaia DSM17938
Bio-K+
Bio-Kult
BNR17
CNCM I-745
DDS-1
De Simone
DuoLac
GanedenBC
I.31
I-3856
KB290
HA-196
LAB4
LacClean
Lactospore
LBSC
LCR35
LGG
LP299v
MF1298
MIMb75
NCFM
Nissle 1917
Paraghurt
Probio-Tec
R0165
SDC 2012, 2013
Symbioflor-2
Symprove
UABla-12
UCC4331
Unique IS-2
Winclove
ATCC SD5221 x LAFT1
BGN4 x AD011 x AD031 x IBS041
GG x LC705 x Bb99 x JS
LA101 x LA102 x LA103 x LA104
M63 x M16V x BB536
NCFM x Bi07
References for Unique IS-2
Madempudi RS, Ahire JJ, Neelamraju J, et al. Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2 vs placebo on the symptoms management of irritable bowel syndrome in adults. Sci Rep. 2019;9:12210. doi:10.1038/s41598-019-48554-x.
Sudha MR, Jayanthi N, Aasin M, et al. Efficacy of Bacillus coagulans Unique IS2 in treatment of irritable bowel syndrome in children: a double-blind, randomized placebo-controlled study. Benef Microbes. 2018;9(4):563-572. doi:10.3920/BM2017.0129.
Madempudi RS, Neelamraju J, Ahire JJ, et al. Bacillus coagulans Unique IS2 in constipation: a double-blind, placebo-controlled study. Probiotics Antimicrob Proteins. 2020;12(1):335-342. doi:10.1007/s12602-019-09542-9.
AEProbio. AEProbio Clinical Guide to Probiotic Products Available in the USA. 2025. Accessed January 31, 2025.
Zhang T, Zhang C, Zhang J, Sun F, Duan L. Efficacy of probiotics for irritable bowel syndrome: a systematic review and network meta-analysis. Front Cell Infect Microbiol. 2022;12:859967. doi:10.3389/fcimb.2022.859967.
So D, Quigley EMM, Whelan K. Probiotics in irritable bowel syndrome and inflammatory bowel disease: review of mechanisms and effectiveness. Curr Opin Gastroenterol. 2023;39(2):103-109. doi:10.1097/MOG.0000000000000902.
McFarland LV, et al. Strain-specific and outcome-specific efficacy of probiotics for the treatment of irritable bowel syndrome: a systematic review and meta-analysis. eClinicalMedicine. 2021;41:101154.
Xie P, Luo M, Deng X, Fan J, Xiong L. Outcome-specific efficacy of different probiotic strains and mixtures in irritable bowel syndrome: a systematic review and network meta-analysis. Nutrients. 2023;15(17):3856. doi:10.3390/nu15173856.